- Posted by admin
- On 20/04/2017
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Epidemiological studies have suggested that there is a genetic component in the development of IBS with reports of clusters in families. There are many studies looking at various gene mutations in IBS families with the conclusion that the evidence does support a modest polygenetic susceptibility in IBS (it can run in families).
Kalantar JS et al Familial aggregation of irritable bowel syndrome a prospective study. GUT 2003; 52: 1703-1707
This is a hard one it’s a bit like the chicken and the egg does the IBS affect the mental health or does the mental health cause the IBS?
The way we work and live our lives brings all kinds of stress.
What I do find with clients is that the worry of their symptoms or worry how their gut is going to behave can be enough to bring on symptoms themselves, independent of what
It is hard to pin point the actual mechanism but there is little doubt there is a complex interaction between stress and IBS.
Visceral pain is a diagnosing factor in IBS, when studies have looked at this IBS sufferers appear to have a heightened response to GI stimulation (abdominal pain).
A Study in the 1970’s looked at the preception of pain in IBS suffers. They compared IBS suffers to non ibs suffers by administered a balloon insertion into their rectum to get them to review their pain experience. They found that the IBS suffers reported heightened pain compared to the non IBS suffers after this procedure.
Ritchie J. Pain from distension of the pelvic colon by inflating a balloon in the Irritable colon syndrome. GUT 1973; 14: 125-132
Previous chronic, or indeed transient inflammation in the GI tract can potentially result in persistent symptoms. This is concluded by a higher amount of Crohns, colitis, diverticular disease patients are 2-3 times higher than the general population to go on to develop IBS symptoms. Also 22% of IBS patients report it started after an episode of gastroenteritis.
Long et al Inflammatory bowel disease, irritable bowel syndrome, or what? A challenge to the functional-organic dichotomy. American journal of Gastroenterology 2010; 105: 1796-1798
So if your gut has been inflamed or irritated in some way then you are at a higher chance of developing IBS symptoms.
This is concluded because some people report their symptoms improve when they perform dietary eliminations. This isn’t something that can be picked up on a skin prick test as it is not a IgE response (Allergic) but more and IgG response (Intolerance) and this can only be detected with food eliminations like removing Gluten, Dairy, FODMAPS.
Specific bacteria strains have been linked to the development of IBS and are thought to maintain low grade inflammation. Studies conclude that it appears to be the ratio of Bifidobacterium and Enterobacteria. BUT it is a bit more complicated than this because it doesn’t always appear to be as easy as adding a probiotic as this evidence isn’t conclusive.
The reason we are developing IBS is varied and multifactorial and can have a big effect on peoples lives. If you are looking for support with this condition the IBS Network is a good place to start.
They have online support and you can call to speak to someone about your condition www.theibsnetwork.org. Also If you are worried that you may have IBS it is best to get checked over by your GP to ensure proper diagnosis.